A diet rich with foods that are high in potassium could help prevent leg cramps.

One of the easiest and most commonly followed methods for preventing and curing leg cramps is increasing the level of potassium in your body. Potassium is an essential mineral that helps keep your kidneys, your skeleton, heart and body muscles healthy and in good working order. Many people have learned that taking a daily potassium supplement can greatly reduce their leg cramps at night.
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Quinine can prevent leg cramps.